Volume 3, Issue 1, January 2018, Page: 1-5
New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies
Mohamed M. Al-Sayed, Chemistry Department, Faculty of Science & Arts Al-Mukhwah, Al-Baha University, Al-Baha, Saudi Arabia
Received: Aug. 24, 2017;       Accepted: Oct. 8, 2017;       Published: Jan. 12, 2018
DOI: 10.11648/j.bmb.20180301.11      View  1418      Downloads  113
Abstract
Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.
Keywords
Pyrano[2,3-c]Pyrazole, Nickel, Oxidation, Catecholase
To cite this article
Mohamed M. Al-Sayed, New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies, Biochemistry and Molecular Biology. Vol. 3, No. 1, 2018, pp. 1-5. doi: 10.11648/j.bmb.20180301.11
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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