Volume 1, Issue 3, November 2016, Page: 27-33
Antimicrobial Potentials of Parkia clappertoniana Jacq, Boswellia dalzielli Hutch and Carica papaya L. Ethanolic Extract on Multi- drug Resistant Diarrheal salmonallae and shigellae Bacteria
Maryam Sani Lawal, Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria
Abdulsalami Mohammed Sani, Department of Biological Sciences, Nigerian Defence Academy, Kaduna, Nigeria
Denwe Samuel Dangmwan, Department of Biological Sciences, Nigerian Defence Academy, Kaduna, Nigeria
Usman Yahaya, Trial Afforestation Research Station, Forestry Research Institute of Nigeria (FRIN), Kaduna, Nigeria
Received: Sep. 9, 2016;       Accepted: Sep. 22, 2016;       Published: Oct. 14, 2016
DOI: 10.11648/j.bmb.20160103.11      View  2780      Downloads  106
Medicinal plants constitute the major component of traditional medicine practiced worldwide due to the economic viability, accessibility, and ancestral experience. Three medicinal plants (Boswelllia dalzielli Hutch, Carica papaya L. and Parkia clappertoniana Jacq) used locally in diarrheal treatment were investigated. This study was carried on isolated and confirmed strains of multi-drug resistant isolates of salmonallae and shigellae bacteria isolated from diarrheal patients in kaduna metropolis, Nigeria. The antidiarrheal activity of the three plant extracts against multidrug resistant strains of Shigella and Salmonella was performed by agar well diffusion method using standard guidelines. The findings indicated that Boswelllia dalzielli, Carica papaya and Parkia clappertoniana had growth inhibitory effect against the tested bacteria. Ethanolic extract of Boswelllia dalzielli exhibited the highest inhibitory effect at 100mg/ml concentration on both Salmonella and Shigella isolates. When the results were statistically analyzed using Duncan's multiple range test (P<0.05), the highest efficacy was recorded with the ethanol extracts of Boswelllia dalzielli (26.00 ± 1.00). On the basis of these findings, it can be assumed that ethanol extracts of Boswelllia dalzielli, Carica papaya and Parkia clappertoniana could be potential sources for antidiarrheal drugs.
Diarrhea, Multidrug Resistance, Medicinal Plants
To cite this article
Maryam Sani Lawal, Abdulsalami Mohammed Sani, Denwe Samuel Dangmwan, Usman Yahaya, Antimicrobial Potentials of Parkia clappertoniana Jacq, Boswellia dalzielli Hutch and Carica papaya L. Ethanolic Extract on Multi- drug Resistant Diarrheal salmonallae and shigellae Bacteria, Biochemistry and Molecular Biology. Vol. 1, No. 3, 2016, pp. 27-33. doi: 10.11648/j.bmb.20160103.11
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